Shaklee Published Manuscripts

(In chronological order)

1. Jenkins MY, Mitchell GV. Biological and biochemical evaluation of commercial powdered protein products. Nutr Rep Int 1981;24(3): p. 499-510.

2. Spiller GA, Wong LG, Whittam JH, Scala J. Correlation of gastrointestinal transit time to fecal weight in adult humans at two levels of fiber intake. Nutr Rep Int 1982;25: p.23-30.

3. Albanese AA, Wein EH, Carroll LA. Effects of a high-protein supplement on body weight and blood constituents of overweight and obese individuals. Nutr Rep Int 1984;29: p. 193-204.

4. Hegenauer J, Strause L, Saltman P, Dann 0, White J, Green R. Transitory hematologic effects of moderate exercise are not influenced by iron supplementation. Eur J Appl Physiol 1983;52: p. 57-61.

5. Ellsworth NM, Hewitt BF, Haskell WL. Nutrient intake of elite male and female Nordic skiers. Physician Sports Med 1985;13: p. 78-92.

6. Jensen CD, Pattison TS, Spiller GA, Whittam JH, Scala J. Repletion and depletion of serum alpha and beta carotene in humans with carrots and an algae-derived supplement. Acta Vitaminol Enzymol 1985;7: p. 189-98.

7. Spiller GA, Pattison TS, Jensen CD, Wong LG, Whittam JH, Scala J. Multivitamin-mineral supplementation: effects on blood chemistries of college-age women. Acta Vitaminol Enzymol 1985;7: p. 217-22.

8. Albanese AA, Lorenze EJ, Edelson AH, et al. Calcium nutrition and skeletal and alveolar bone health. Nutr Rep Int 1985;31: p. 741-55.

9. Luo XM, Wei HJ, Yang CL, et al. Bioavailability of selenium to residents in a low-selenium area of China. Am J Clin Nutr 1985;42: p. 439-48.

10. Albanese AA, Edelson AH, Lorenze EJ, Wein EH, Carroll LA. Effect of age and fractures on bone loss and calcium needs of women 45-85+ years of age. Nutr Rep Int 1985;31: p. 1093-1115.

11. Thompson D, Lemaster C, Allen R, Whittam JH. Evaluation of relative shampoo detergency. J Soc Cosmet Chem 1985;36: p. 271-86.

12. Luo XM, Wei HJ, Yang CL, et al. Selenium intake and metabolic balance of 10 men from a low selenium area of China. Am J Clin Nutr 1985;42: p. 31-7.

13. Jensen CD, Spiller GA, Pattison TS, Whittam JH, Scala J. Acute effects of dietary carotenes on serum alpha and beta carotene in humans. Nutr Rep Int 1986;33: p. 117-22.

14. Spiller GA, Story JA, Wong LG, et al. Effect of increasing levels of hard wheat fiber on fecal weight, minerals, steroids and gastrointestinal transit time in healthy young women. J Nutr 1986;116: p. 778-85.

15. Haymes EM, Puhl JL, Temples TE. Training for cross-country skiing and iron status. Med Sci Sports Med 1986;18: p. 162-7.

16. Hagan RD, Upton SJ, Wong LG, Whittam JH. The effects of aerobic conditioning and/or caloric restriction in overweight men and women. Med Sci Sports Exer 1986;18: p. 87-94.

17. Jensen CD, Howes TW, Spiller GA, Pattison TS, Whittam JH, Scala J. Observations on the effects of ingesting cis- and trans-beta carotene isomers on human serum concentrations. Nutr Rep Int 1987;35: p. 413-22.

18. Spiller GA, Jensen CD, Pattison TS, Chuck CS, Whittam JH, Scala J. Effect of protein dose on serum glucose and insulin response to sugars. Am J Clin Nutr 1987;46: p. 474‑80.

19. Superko HR, Haskell WL, Sawrey-Kubicek L, Farquhar JW. Effects of solid and liquid guar gum on plasma cholesterol and triglyceride concentrations in moderate hypercholesterolemia. Am J Cardiol 1988;62: p. 51-5.

20. Jensen CD, Spiller GA, Wookey VJ, Wong LG, Whittam JH, Scala J. Plasma lipids on three levels of fish oil intake in healthy human subjects. Nutr Rep Int 1988;38: p. 165-72.

21. Nadel ER, Bussolari SR. The Daedalus project: physiological problems and solutions. Am Scientist 1988;76: p. 351-60.

22. Jenkins DJ, Wolever TM, Spiller GA, et al. Hypocholesterolemic effect of vegetable protein in a hypocaloric diet. Atherosclerosis 1989;78: p. 99-107.

23. Wiess R. The Physiology of Human-Powered Flight. Sci News 1990;137(9): p. 140.

24. Haskell WL, Spiller GA, Jensen CD, Ellis BK, Gates JE. Role of water-soluble dietary fiber in the management of elevated plasma cholesterol in healthy subjects. Am J Cardiol 1992;69: p. 433-9.

25. Zawadzki KM, Yaspelkis III BB, Ivy JL. Carbohydrate-protein complex increases the rate of muscle glycogen storage after exercise. J Appl Physiol 1992;72: p. 1854-9.

26. Jensen CD, Zaltas ES, Whittam JH. Dietary intakes of male endurance cyclists during training and racing. J Am Diet Assoc 1992;92: p. 986-8.

27. Jensen CD, Spiller GA, Gates JE, Miller A, Whittam JH. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12: p. 147-54.

28. Greenleaf JE, et al. Vascular uptake of rehydration fluids in hypohydrated men at rest and during exercise. NASA Tech Memo 1992(August): p. 1039-42.

29. Yaspelkis III BB, Patterson TS, Anderla PA, Ding Z, Ivy JL. Carbohydrate supplementation spares muscle glycogen during variable-intensity exercise. J Appl Physiol 1993;75: p. 1477-85.

30. Chandler RM, Byrne HK, Patterson JG, Ivy JL. Dietary supplements affect the anabolic hormones after weight-training exercise. J Appl Physiol 1994;76: p. 839-45.

31. Greenleaf JE, et al. Hypervolemia in men from drinking hyperhydration fluids at rest and during exercise. NASA Tech Memo 1994(December): p. 46-57.

32. Greenleaf JE, et al. Drink composition and cycle-ergometer endurance in men: carbohydrate, Na+, osmolality. NASA Tech Memo 1996(November): p. 46-50.

33. Greenleaf JE, Jackson CG, Lawless 0. CD4+/CD8+ T-lymphocyte ratio: effects of rehydration before exercise in dehydrated men. Med Sci Sports Exer 1995;27: p. 194-9.

34. Rachui SR, Duke MA, Allen R. Use of the MatTek EPI-100 in vitro system to screen antioxidant efficacy. J Toxicol Cut Ocular Toxicol 1995;14: p. 237-50.

35. Fox AA, et al. Effects of diet and disease risk factors in moderately obese older women. Am J Clin Nutr 1996. 63(2): p. 225-33.

36. Geelen G, Greenleaf JE, Keil LC. Drinking-induced plasma vasopressin and norepinephrine changes in dehydrated humans. J Clin Endocrinol Metab 1996;81: p. 2131-35.

37. Jensen CD, Haskell W, Whittam JH. Long-term effects of water-soluble dietary fiber in the management of hypercholesterolemia in healthy men and women. Am J Cardiol 1997;79: p. 34-7.

38. Grant KE, et al. Chromium and exercise training: effect on obese women. Med Sci Sports Exerc 1997;29(8): p. 992-8.

39. Greenleaf JE, et al. Pre-exercise hypervolemia and cycle ergometer endurance in men. Biol Sport 1997;14(2): p. 103‑14.

40. Broughton KS, et al. Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production. Am J Clin Nutr 1997;65(4): p. 1011-7.

41. Greenleaf JE, et al. Hypervolemia in men from fluid ingestion at rest and during exercise. Aviat Space Environ Med 1998;69(4): p. 374-86.

42. Thompson JL, et al. Effects of diet and exercise on energy expenditure in postmenopausal women. Am J Clin Nutr 1997;66(4): p. 867-73.

43. Dubuc GR, et al. Changes of serum leptin and endocrine and metabolic parameters after 7 days of energy restriction in men and women. Metabolism 1998;47(4): p. 429-34.

44. Roberts RL, Greene JA. Clinical Testing of Personal Care Products. The Chemist 1999;Nov/Dec: p. 23-26.

45. Greenleaf JE, et al. Plasma sodium-osmotic dissociation and hormonal interaction with drinking-induced hypervolemia at 2800 m altitude. Aviat Space Environ Med 2001;72(6): p. 522-8.

46. Barrett BP, et al. Treatment of the common cold with unrefined echinacea. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 2002;137(12): p. 939-46.

47. Jensen C, et al. Long-term effects of nutrient intervention on markers of bone remodeling and calciotropic hormones in late-postmenopausal women. Am J Clin Nutr 2002;75(6): p. 1114-20.

48. Schaffer DM, et al. Nonvitamin, nonmineral supplement use over a 12-month period by adult members of a large health maintenance organization. J Am Diet Assoc 2003;103(11): p. 1500-5.

49. Kaji K, et al. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol 2004;39(9): p. 873-8.

50. Ushiroyama T, et al. A pilot study of a Kampo formula, EH0202, with intriguing results for menopausal symptoms. J Altern Complement Med 2004;10(2): p. 397-9.

51. Ushiroyama T, et al. Clinical efficacy of EH0202, a Kampo formula, on the health of middle-aged women. Am J Chin Med 2004;32(5): p. 755-70.

52. Kubo M, Hasimoto Y, and Yoshida S. The effect of health food containing EH0202 on physical and mental symptoms accompanying menstruation in women with premenstrual syndrome (PMS). Clinical Pharmacology and Therapy 2004;14(2): p. 129-42.

53. Schirmer MA, Phinney SD. {gamma}-Linolenate Reduces Weight Regain in Formerly Obese Humans. J Nutr 2007;137(6): p. 1430-5.

54. Block G, Jensen CD, Norkus EB, Dalvi TB, Wong LG, McManus JF, Hudes ML. Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study. Nutrition J 2007;(6)30: p. 1-11.

55. Lunetta S, Roman M. Determination of coenzyme Q10 content in raw materials and dietary supplements by high-performance liquid chromatography-UV: Collaborative study. J AOAC Int 2008;91(4): p. 702-8.

56. Westcott WL, Martin WF, La Rosa Loud R, and Stoddard S. Research update: protein and body composition. Fitness Management May 2008: p. 50-3.

57. Palermo LM, et al. Human parainfluenza virus infection of the airway pithelium: viral hemagglutinin-neuraminidase regulates fusion protein activation and modulates infectivity. J Virol 2009;83(13): p. 6900-8.

58. Maki K.C., et al. Serum 25-hydroxyvitamin D is independently associated with high-density lipoprotein cholesterol and the metabolic syndrome in men and women. J Clin Lipidol. 2009;3:289-296.

59. Maki KC, Rubin MR, Wong LG, McManus JF, Jensen CD, Lawless A. Effects of vitamin D supplementation on 25-hydroxyvitamin D, high-density lipoprotein cholesterol, and other cardiovascular disease risk markers in subjects with elevated waist circumference. Int J Food Sci Nutr. 2011 Jun; 62(40):318-27.

60. Ghanim H, et al. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory response to a high-fat, high-carbohydrate meal. J Clin Endocrinol Metab. 2011 May;96(5):1409-14.

61. McHugh RT, Hollins JL, Lau FC, Daggy BP. Effect of combined AREDS2 supplementation and a polyphenol preparation on dry age-related macular degeneration (AMD): analysis of case studies. Presented at the American Society for Nutrition’s Advances & Controversies in Clinical Nutrition conference, National Harbor, MD, 2014 Dec.

62. Lau FC, Daggy BP, McManus JF. Effect of a structured meal replacement program on weight loss: an eight-week mobile-app assisted intervention. Presented at the American College of Nutrition’s 55th annual conference, San Antonio, TX, 2014 Oct. JACN 33;5: p. 414.

63. McManus JF, Lau FC, Daggy BP. Outcomes of a 3-month Employee Wellness weight-loss challenge: a physician-supervised, structured meal replacement program. Presented at the American College of Nutrition’s 55th annual conference, San Antonio, TX, 2014 Oct. JACN 33;5: p. 414.

64. Harley CB, Chan U, Blauwkamp M, Lau FC, McManus JF, Watson D, Hytopoulos E, Daggy BP. Cross-sectional analysis of telomere length in people 33-80 years of age: effects of dietary supplementation. Presented at the American College of Nutrition’s 55th annual conference, San Antonio, TX, 2014 Oct. JACN 33;5: p. 414.

65. Lau FC, McManus JF, Daggy BP. Effect of an online, mobile app-mediated structured meal replacement program on weight management: outcomes in a real world setting. Presented at the Obesity Society annual conference, Boston, MA. 2014 Nov.

66. Fisher L, Ianiro T, Lau FC, Wang H, Daggy BP. Synergistic effects of phenolic mixtures in human cell models of aging. Presented at the Experimental Biology conference, Boston, MA. 2015 Apr. FASEB J 29;1: 608.36.

67. Wang H, Daggy BP. Immuno-stimulatory activities of a blend of natural extracts in human immune cells. Presented at the Experimental Biology conference, Boston, MA. 2015 Apr. FASEB J 29;1: 593.7.

Other Scientific Publications

(In chronological order)

1. Newman MB, Soparkar PM, Depaola PF, Poovaiah BP. Clinical study of the effectiveness of an organic dentifrice for stain removal. J Dental Res 1980:59: p. 276 (abstr).

2. Albanese AA, Lorenze EJ, Scala J, Wein EH. Effects of calcium and micronutrients on premenopausal and postmenopausal bone loss. J Am Med Assoc 1980;244: p. 1915 (abstr).

3. Poovaiah BP, Rider JA, Scala J. The kinetics of vitamin C in human blood plasma from vitamin C supplements. Fed Proc 1980:39: p. 557 (abstr).

4. Soparkar PM, Newman MB, Depaola PF, Poovaiah BP. Clinical study of the effect of an organic dentifrice on gingivitis and plaque formation. J Dental Res 1980:59: p. 275 (abstr).

5. Pattison T, Allen R, and Ashley H. Automated Testing of Slowly Changing Levels of Analytes in Mixtures. Clin Chem 1982;28(7): p. 1613.

6. Chuck CS, et al. Postprandial glycemia on two sweet confections with different carbohydrate patterns. Fed Proc 1982;41(398).

7. Spallholz JE, Freitas R, Holm J, Whittam JH. Cytologic activity of selenium compounds and glutathione peroxidase assessed by scanning electron microscopy. Fed Proc 1982:41: p. 529 (abstr).

8. Story JA, et al. Modification of human fecal steroid excretion by a dietary fiber supplement. Fed Proc 1983;42(4): p. 1062.

9. Albanese M, Wein EH, Whittam JH, Scala J. Effects of vitamin/mineral intervention on increasing bone density of postmenopausal women. 4th European Nutrition Conference, The Hague, Netherlands 1983 (abstr).

10. Whittam JH, Chuck CS, Ikemiya C, et al. Weight loss on a combined regimen of formula diet and traditional food. 4th International Congress on Obesity, New York City 1983 (abstr).

11. Whittam JH, et al. Weight Management Program Designed for and administered by Non-Professional Leaders. 4th European Nutrition Conference, 1983.

12. Minear AL, Blankenbaker GM, and Sacks PV. 630 Kcal formula diet versus 1,200 Kcal balanced deficit diet: comparison of weight loss and safety. J Am Diet Assoc 1983. p. 83.

13. Hoage CM, Fediuk ME. Compulsive eating, depression and failure to complete a behavioral group weight loss program. 4th International Congress on Obesity, 1983.

14. Spiller GA, Ashley H, Whittam JH, Scala J. Postprandial hyperglycemia on a complete liquid formula diet, its carbohydrate fraction and glucose. International Congress of Diabetes and Nutrition, Crete, Greece 1983 (abstr).

15. Spiller GA, Wong LG, Nunes JD, et al. Effect of four levels of hard wheat bran on fecal composition and transit time in healthy young women. Fed Proc 1984;43: p. 392 (abstr).

16. Luo XM, Yang CL, Wei HJ, et al. Selenium intake and metabolic balance in 10 men consuming self-selected diets in a selenium-deficient area of Hebei Province, People’s Republic of China. Fed Proc 1984;43: p. 473 (abstr).

17. Wei HJ, Lua XM, Yang CL, et al. Effect of selenium supplements on the selenium levels and glutathione peroxidase activity of residents in a selenium-deficient area of Hebei Province, People’s Republic of China. Fed Proc 1984;43: p. 473 (abstr).

18. Dronkert A, Spiller GA, Whittam JH, Scala J. Safety and effect on weight, hemoglobin A-1C, serum glucose and blood pressure of a liquid formula diet combined with traditional food in adult diabetic patients: A pilot study. Diabetes and Hypertension Meeting, Bern, Switzerland 1984 (abstr).

19. Spiller GA, Ashley H, Chuck CS, Pattison TS, Whittam JH, Scala J. Effect on postprandial glycemia of a formula diet and its carbohydrate fraction with or without protein and fat. Am J Clin Nutr 1984;39: p. 671 (abstr).

20. Scala J, Wong LG. The coach and nutritionist - a partnership in performance. A case study - applied nutrition with the US Ski Team and Mount Everest Expedition. In: Shrimpton OH, Ottaway PB, eds. Nutrition in Sport: Proceedings of a National Symposium held at the Institute of Directors, London 1985; p. 76‑83.

21. Pattison TS, Spiller GA, Jensen CD, Whittam JH, Scala J. Comparison of serum beta carotene repletion with two levels of carrots and an algae-derived product in healthy adult humans. Fed Proc 1985;44: p. 771 (abstr).

22. Story JA, Petro MS, Spiller GA, Wong LG, Whittam JH, Scala J. Modification of human fecal steroid excretion by a dietary fiber supplement. Fed Proc 1983;42: p. A4512 (abstr).

23. Spiller GA, Pattison TS, Jensen CD, Wong LG, Whittam JH, Scala J. Some effects of vitamin and mineral supplementation in healthy young women. Fed Proc 1985;44: p. 1283 (abstr).

24. Spiller GA, Pattison TS, Jensen CD, Whittam JH, Scala J. Effect of protein quantity and quality on the serum glucose response to the sugars of a formula diet. Am J Clin Nutr 1985;41: p. 854 (abstr).

25. Jensen CD, Howes TW, Spiller GA, Scala J. Observations on the effects in humans of cis- and trans-beta carotene isomers. Am J Clin Nutr 1986;43: p. 689 (abstr).

26. Wookey VJ, Sacks PV, Jensen CD, Scala J, Spiller GA. Effect of low-calorie diets on retinal-binding protein (RBP) status in women. Am Diabetes Assoc 47th Scientific Sessions Meeting, Indianapolis 1987 (abstr).

27. Spiller GA, Jensen CD, Scala J. Effect of low dose omega-3 fatty acids on plasma fatty acids and lipids. Am J Clin Nutr 1987;45: p. 857.

28. Jensen CD, Briggs GM. Dietary supplements. J Am Med Assoc 1987;258:908-10.

29. Wookey V, et al. Effect of low-calorie diets on retinol-binding protein (RBP) status in women. Am Diabetes Assoc 47th Scientific Sessions Meeting, 1987.

30. Spiller GA, Jensen CD, Whittam J. Effect of high calcium intake on magnesium excretion. FasEB J, 1988;2(6): p. A1099.

31 Whittam J. Salon testing: art or science? Cosmetics and Toiletries 1988;103: p. 43-6.

32. Jensen CD, Dronkert A, Whittam J. Effects of graded levels of beta-carotene on skin yellowing in healthy humans. FASEB J 1989;3(3): p. A465.

33. Long L, Jensen C, Whittam J. The effects of sodium:carbohydrate (Na:carb) ratios in rehydration beverages (RB) on plasma (PG), osmolality (PO), volume (PV), and subject tolerance (ST). FASEB J 1990;4(3): p. A381.

34. Spiller G, et al. The effect of three doses of a water soluble dietary fiber (WSDF) mixture on plasma cholesterol in humans. International Symposium on Multiple Risk Factors in Cardiovascular Disease, 1990: p. 89.

35. Spiller G, et al. Plasma cholesterol-lowering efficacy of a mixture of water soluble dietary fibers (WSDF) compared to guar gum. International Symposium on Multiple Risk Factors in Cardiovascular Disease, 1990: p. 90.

36. Spiller G, et al. The relationship of water soluble dietary fiber (WSDF) structure to plasma cholesterol-lowering efficacy in humans. International Symposium on Multiple Risk Factors in Cardiovascular Disease, 1990: p. 89.

37. Greenleaf JE, et al. Vascular uptake of rehydration fluids in Resting hypohydrated men. FASEB J 1991;5: p. A1147 (abstr).

38. Jensen C, et al. The effect of acacia gum versus a mixture of water-soluble dietary fibers on blood lipids in humans. FASEB J, 1992;6: p. A1654.

39. Foster VL, Sirotniak AC. Glucose-electrolyte ingestion: influence on endurance factors in highly trained female cyclists. Med Sci Sports Exerc 1992;24(5): p. S121.

40. Butterfield G, Borchers J. Response of serum glucose and insulin to meals of various compositions fed after exercise. Sports Med Training Rehab, 1993;4: p. 304.

41. Fox A, et al. Effects of diet and exercise on weight loss, fat distribution and blood lipid changes in moderately obese older women. Med Sci Sports Exerc, 1994;26(5): p. S58.

42. Thompson D, et al. The effect of diet and exercise on basal metabolic rate in older women. Thompson, Moynihan, Gylfadottir, Vizoli, Butterfield. Med Sci Sports Exerc, 1994;26(2): p. S79. 43.

43. Whittam J, Jensen C, Hudson T. Alfalfa, vitamin E, and autoimmune disorders. Am J Clin Nutr, 1995;62(5): p. 1025‑6.

44. Spiller G, Bruce B, Jensen C. Homocysteine lowering in men and women with normal plasma homocysteine levels. J Am Coll Nutr, 1998;17: p. 530.

45. Spiller G, et al. Effect of long-term vitamin-mineral supplements on immune response in older healthy adults. J Am Coll Nutr, 1998;17: p. 511.

46. Bruce B, et al. Effects of supplemental soy protein in hypercholesterolemic postmenopausal women. Cardiovascular Health: A National Conference, 1998: p. 143.

47. Jenkins AL, Block G. Effect of nutrient intervention on bone mineral density and biomarkers of bone remodeling. Am J Epidemiol. 1999;149(11): p. S30.

48. Wallock LM, et al. Improvement in folate indices in blood and seminal plasma following vitamin supplementation in smokers and nonsmokers. FASEB J, 1999;13: p. A890.

49. Manning P. An herbal approach to ease the transition to menopause. Nutrition in Complementary Care, 2000;2(2): p. 3.

50. Debernardi D, Subramanian S, Hegenauer J. Enhancement of folic acid dissolution in solid dosage forms of dietary supplements. ACS Symp Ser, 2002.

51. Yoshida S, Ushiroyama T, Zhang P. Clinical study of Shaklee EH0202 in menopausal patients. International Congress on Natural Products Research, 2004.

52. Honda T, Ianiro T, Ubillas R, Mergens W. Development of a reliable HPLC test method for analysis of NAC. Association of Analytical Communities international meeting, 2006: p. 1308.

53. Maki KC, et al. Serum 25-hydroxyvitamin D is an independent predictor of high density lipoprotein cholesterol and metabolic syndrome in men and women. National Lipid Association Annual Scientific Sessions 2009.

54. Maki KC, et al. Effects of vitamin D supplementation on 25-hydroxyvitamin D and markers of cardiovascular disease risk in subjects with elevated waist circumference. National Lipid Association Scientific Sessions, 2010.